Item Type | Name |
Concept
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Alleles
|
Concept
|
Amino Acid Sequence
|
Concept
|
Computer Simulation
|
Concept
|
Genes
|
Concept
|
Sex Characteristics
|
Concept
|
Population Surveillance
|
Concept
|
Reference Standards
|
Concept
|
Uterine Neoplasms
|
Concept
|
Cohort Studies
|
Concept
|
Regulatory Sequences, Nucleic Acid
|
Concept
|
Smoking
|
Concept
|
Software
|
Concept
|
Spatial Behavior
|
Concept
|
Genome
|
Concept
|
United States
|
Concept
|
Case-Control Studies
|
Concept
|
Alternative Splicing
|
Concept
|
Ubiquitin Thiolesterase
|
Concept
|
Genes, X-Linked
|
Concept
|
Sample Size
|
Concept
|
Simvastatin
|
Concept
|
Metabolic Syndrome
|
Concept
|
Genetic Association Studies
|
Concept
|
Genetic Pleiotropy
|
Concept
|
Exome
|
Concept
|
Intercellular Signaling Peptides and Proteins
|
Concept
|
Systems Biology
|
Concept
|
Biological Specimen Banks
|
Concept
|
3' Untranslated Regions
|
Concept
|
Schizophrenia
|
Concept
|
Stress Disorders, Post-Traumatic
|
Concept
|
Ubiquitin-Protein Ligases
|
Concept
|
Sex Factors
|
Concept
|
Adaptor Proteins, Signal Transducing
|
Concept
|
Models, Statistical
|
Concept
|
Genome, Human
|
Concept
|
Survival Rate
|
Concept
|
Tumor Suppressor Proteins
|
Concept
|
Transcriptome
|
Concept
|
Genome-Wide Association Study
|
Concept
|
RNA, Small Interfering
|
Concept
|
Molecular Sequence Annotation
|
Concept
|
National Heart, Lung, and Blood Institute (U.S.)
|
Concept
|
Receptors, Urokinase Plasminogen Activator
|
Concept
|
Data Interpretation, Statistical
|
Concept
|
Drug Screening Assays, Antitumor
|
Concept
|
Epistasis, Genetic
|
Concept
|
Longitudinal Studies
|
Concept
|
Organ Specificity
|
Concept
|
Retrospective Studies
|
Concept
|
Ribonucleoproteins, Small Nuclear
|
Concept
|
Sequence Analysis, RNA
|
Concept
|
Disease-Free Survival
|
Concept
|
Polymorphism, Single Nucleotide
|
Concept
|
Quantitative Trait Loci
|
Concept
|
Genetic Loci
|
Academic Article
|
Accounting for animal movement in estimation of resource selection functions: sampling and data analysis.
|
Academic Article
|
Population differences in microRNA expression and biological implications.
|
Academic Article
|
Platinum sensitivity-related germline polymorphism discovered via a cell-based approach and analysis of its association with outcome in ovarian cancer patients.
|
Academic Article
|
Functional consequences of PRPF39 on distant genes and cisplatin sensitivity.
|
Academic Article
|
On sharing quantitative trait GWAS results in an era of multiple-omics data and the limits of genomic privacy.
|
Academic Article
|
Mixed effects modeling of proliferation rates in cell-based models: consequence for pharmacogenomics and cancer.
|
Academic Article
|
Targeting the urokinase plasminogen activator receptor inhibits ovarian cancer metastasis.
|
Academic Article
|
Comprehensive evaluation of the contribution of X chromosome genes to platinum sensitivity.
|
Academic Article
|
An eQTL-based method identifies CTTN and ZMAT3 as pemetrexed susceptibility markers.
|
Academic Article
|
Identification of novel germline polymorphisms governing capecitabine sensitivity.
|
Academic Article
|
Germline polymorphisms discovered via a cell-based, genome-wide approach predict platinum response in head and neck cancers.
|
Academic Article
|
Whole-genome studies identify solute carrier transporters in cellular susceptibility to paclitaxel.
|
Academic Article
|
Genetic architecture of microRNA expression: implications for the transcriptome and complex traits.
|
Academic Article
|
Comprehensive genetic analysis of cytarabine sensitivity in a cell-based model identifies polymorphisms associated with outcome in AML patients.
|
Academic Article
|
Trans-population analysis of genetic mechanisms of ethnic disparities in neuroblastoma survival.
|
Academic Article
|
Integrative genomics: quantifying significance of phenotype-genotype relationships from multiple sources of high-throughput data.
|
Academic Article
|
Genome-wide interrogation of longitudinal FEV1 in children with asthma.
|
Academic Article
|
The impact of microRNA expression on cellular proliferation.
|
Academic Article
|
Poly-omic prediction of complex traits: OmicKriging.
|
Academic Article
|
Integrative analyses of genetic variation, epigenetic regulation, and the transcriptome to elucidate the biology of platinum sensitivity.
|
Academic Article
|
Genome-wide discovery of genetic variants affecting tamoxifen sensitivity and their clinical and functional validation.
|
Academic Article
|
Protein quantitative trait loci identify novel candidates modulating cellular response to chemotherapy.
|
Academic Article
|
Genetic and epigenetic variants contributing to clofarabine cytotoxicity.
|
Academic Article
|
Identification and functional characterization of G6PC2 coding variants influencing glycemic traits define an effector transcript at the G6PC2-ABCB11 locus.
|
Academic Article
|
Quantitative allelic test--a fast test for very large association studies.
|
Academic Article
|
EPS8 inhibition increases cisplatin sensitivity in lung cancer cells.
|
Academic Article
|
Integrating cell-based and clinical genome-wide studies to identify genetic variants contributing to treatment failure in neuroblastoma patients.
|
Academic Article
|
Association of body mass index and outcomes after major lung resection.
|
Academic Article
|
Pleiotropic genes for metabolic syndrome and inflammation.
|
Academic Article
|
Establishment of CYP2D6 reference samples by multiple validated genotyping platforms.
|
Academic Article
|
A gene-based association method for mapping traits using reference transcriptome data.
|
Academic Article
|
C. elegans and mutants with chronic nicotine exposure as a novel model of cancer phenotype.
|
Academic Article
|
Imputing Gene Expression in Uncollected Tissues Within and Beyond GTEx.
|
Academic Article
|
The genetic architecture of type 2 diabetes.
|
Academic Article
|
Survey of the Heritability and Sparse Architecture of Gene Expression Traits across Human Tissues.
|
Academic Article
|
A Low-Frequency Inactivating AKT2 Variant Enriched in the Finnish Population Is Associated With Fasting Insulin Levels and Type 2 Diabetes Risk.
|
Academic Article
|
Genomic analyses identify hundreds of variants associated with age at menarche and support a role for puberty timing in cancer risk.
|
Grant
|
Genomic and Transcriptomic Analysis of Emphysema and Subclinical ILD
|
Academic Article
|
Annotation-free quantification of RNA splicing using LeafCutter.
|
Academic Article
|
Exploring the phenotypic consequences of tissue specific gene expression variation inferred from GWAS summary statistics.
|
Academic Article
|
ukbREST: efficient and streamlined data access for reproducible research in large biobanks.
|
Academic Article
|
Erratum: Sequence data and association statistics from 12,940 type 2 diabetes cases and controls.
|
Academic Article
|
Genetic architecture of gene expression traits across diverse populations.
|
Academic Article
|
Erratum to: A multi-stage genome-wide association study of uterine fibroids in African Americans.
|
Academic Article
|
Sequence data and association statistics from 12,940 type 2 diabetes cases and controls.
|
Academic Article
|
A multi-stage genome-wide association study of uterine fibroids in African Americans.
|
Academic Article
|
Trans-ethnic predicted expression genome-wide association analysis identifies a gene for estrogen receptor-negative breast cancer.
|
Academic Article
|
A Transcriptome-Wide Association Study Among 97,898 Women to Identify Candidate Susceptibility Genes for Epithelial Ovarian Cancer Risk.
|
Academic Article
|
Multiethnic meta-analysis identifies ancestry-specific and cross-ancestry loci for pulmonary function.
|
Academic Article
|
Functionally oriented analysis of cardiometabolic traits in a trans-ethnic sample.
|
Academic Article
|
Integrating predicted transcriptome from multiple tissues improves association detection.
|
Academic Article
|
Opportunities and challenges for transcriptome-wide association studies.
|
Academic Article
|
Gene expression imputation across multiple brain regions provides insights into schizophrenia risk.
|
Academic Article
|
Imputed gene associations identify replicable trans-acting genes enriched in transcription pathways and complex traits.
|
Academic Article
|
Shared and distinct genetic risk factors for childhood-onset and adult-onset asthma: genome-wide and transcriptome-wide studies.
|
Academic Article
|
Publisher Correction: Gene expression imputation across multiple brain regions provides insights into schizophrenia risk.
|
Academic Article
|
A Trans-Ethnic Genome-Wide Association Study of Uterine Fibroids.
|
Academic Article
|
Genetic regulatory variation in populations informs transcriptome analysis in rare disease.
|
Academic Article
|
Analysis of Genetically Regulated Gene Expression Identifies a Prefrontal PTSD Gene, SNRNP35, Specific to Military Cohorts.
|
Academic Article
|
CORE GREML for estimating covariance between random effects in linear mixed models for complex trait analyses.
|
Academic Article
|
PhenomeXcan: Mapping the genome to the phenome through the transcriptome.
|
Academic Article
|
sn-spMF: matrix factorization informs tissue-specific genetic regulation of gene expression.
|
Academic Article
|
Cell type-specific genetic regulation of gene expression across human tissues.
|
Academic Article
|
Impact of admixture and ancestry on eQTL analysis and GWAS colocalization in GTEx.
|
Academic Article
|
The impact of sex on gene expression across human tissues.
|
Academic Article
|
Fine-mapping and QTL tissue-sharing information improves the reliability of causal gene identification.
|
Academic Article
|
Transcriptomic signatures across human tissues identify functional rare genetic variation.
|
Academic Article
|
Probabilistic colocalization of genetic variants from complex and molecular traits: promise and limitations.
|
Academic Article
|
Exploiting the GTEx resources to decipher the mechanisms at GWAS loci.
|
Academic Article
|
A scalable unified framework of total and allele-specific counts for cis-QTL, fine-mapping, and prediction.
|
Academic Article
|
Population-scale tissue transcriptomics maps long non-coding RNAs to complex disease.
|
Academic Article
|
Pleiotropy-guided transcriptome imputation from normal and tumor tissues identifies candidate susceptibility genes for breast and ovarian cancer.
|
Academic Article
|
Polygenic transcriptome risk scores (PTRS) can improve portability of polygenic risk scores across ancestries.
|
Academic Article
|
Protein prediction for trait mapping in diverse populations.
|
Academic Article
|
Polygenic transcriptome risk scores for COPD and lung function improve cross-ethnic portability of prediction in the NHLBI TOPMed program.
|
Academic Article
|
Fine-mapping studies distinguish genetic risks for childhood- and adult-onset asthma in the HLA region.
|
Academic Article
|
Discerning asthma endotypes through comorbidity mapping.
|
Academic Article
|
Probabilistic integration of transcriptome-wide association studies and colocalization analysis identifies key molecular pathways of complex traits.
|
Academic Article
|
Multivariate adaptive shrinkage improves cross-population transcriptome prediction for transcriptome-wide association studies in underrepresented populations.
|
Concept
|
Ubiquitin-Specific Peptidase 7
|
Academic Article
|
A joint transcriptome-wide association study across multiple tissues identifies candidate breast cancer susceptibility genes.
|
Academic Article
|
Predicted Proteome Association Studies of Breast, Prostate, Ovarian, and Endometrial Cancers Implicate Plasma Protein Regulation in Cancer Susceptibility.
|
Academic Article
|
Predicting molecular mechanisms of hereditary diseases by using their tissue-selective manifestation.
|
Academic Article
|
Revealing polygenic pleiotropy using genetic risk scores for asthma.
|
Academic Article
|
Multivariate adaptive shrinkage improves cross-population transcriptome prediction and association studies in underrepresented populations.
|
Academic Article
|
On the problem of inflation in transcriptome-wide association studies.
|
Academic Article
|
Transcriptome-wide association study of the plasma proteome reveals cis and trans regulatory mechanisms underlying complex traits.
|